Nandrolone Decanoate
Nandrolone Decanoate 250 mg/mL, commonly known as Deca-Durabolin, is a powerful anabolic steroid renowned for its ability to promote significant muscle growth and enhance recovery. This long-acting injectable formulation provides sustained release, allowing for effective dosing with fewer injections. Nandrolone Decanoate is particularly valued for its ability to improve nitrogen retention and protein synthesis, leading to increased lean muscle mass. Additionally, it has been shown to support joint health and reduce inflammation, making it a popular choice among athletes and bodybuilders. With minimal estrogenic effects, Nandrolone Decanoate is ideal for those seeking to maximize their gains while minimizing potential side effects.
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Description
ACTIVE INGREDIENT
Each mL contains:
- Nandrolone Decanoate 250 mg
DESCRIPTION
Nandrolone Decanoate 250 mg is an injectable anabolic steroid containing nandrolone, a synthetic derivative of testosterone. It is formulated as an oil-based solution for intramuscular injection. Nandrolone Decanoate is known for its potent anabolic effects and relatively low androgenic properties, making it a popular choice for promoting muscle growth, increasing red blood cell production, and enhancing recovery in bodybuilding and sports.
PHARMACOLOGICAL PROPERTIES
Mechanism of Action: Nandrolone binds to androgen receptors, stimulating protein synthesis, increasing nitrogen retention, and promoting muscle growth. It enhances red blood cell production and improves oxygen-carrying capacity, contributing to increased endurance and muscle recovery.
Pharmacokinetics:
- Absorption: Nandrolone Decanoate is slowly released after intramuscular injection, providing a prolonged effect.
- Distribution: It is distributed throughout body tissues, with a high affinity for muscle tissues and plasma proteins.
- Metabolism: Primarily metabolized in the liver.
- Excretion: Excreted through urine, mainly as metabolites.
INDICATIONS
Nandrolone Decanoate 250 mg is indicated for:
Management of anemia: Associated with chronic renal failure.
Treatment of muscle-wasting conditions: To preserve lean muscle mass in patients with chronic debilitating diseases (e.g., HIV/AIDS, cancer).
Adjunct therapy in osteoporosis: To increase bone density in postmenopausal women.
Performance enhancement: In bodybuilding and athletics, it is used to enhance muscle mass, strength, and recovery.
DOSAGE AND ADMINISTRATION
Dosage:
- Medical Use (Anemia and Osteoporosis): 50–100 mg every 1–4 weeks, as directed by the healthcare provider.
- Anabolic/Bodybuilding Use: Common doses range from 200 mg to 600 mg weekly. Dosage may vary depending on the user’s experience, goals, and tolerance.
Administration:
- Administer via deep intramuscular injection, typically into the gluteal muscle. Rotate injection sites regularly to avoid irritation or pain. The oily solution should be injected slowly to minimize discomfort.
CONTRAINDICATIONS
-
Hypersensitivity to nandrolone or any component of the formulation.
- Pregnancy and lactation (Pregnancy Category X).
- Active breast cancer in females or suspected prostate cancer in males.
- Severe cardiovascular, renal, or hepatic disease.
- Hypercalcemia (elevated blood calcium levels).
WARNINGS AND PRECAUTIONS
1. Hepatic Effects: Nandrolone Decanoate may cause liver toxicity, although it is less hepatotoxic than oral anabolic steroids. Liver function should be monitored periodically during long-term use.
2. Cardiovascular Risks: Anabolic steroids may increase the risk of cardiovascular events such as hypertension, myocardial infarction, or stroke. Regular monitoring of blood pressure and lipid profiles is advised.
3. Androgenic Effects: Prolonged use of nandrolone may cause androgenic side effects, including acne, male pattern baldness, and virilization in women (e.g., deepened voice, facial hair growth). Use with caution in female patients
.
4. Suppression of Endogenous Testosterone: Nandrolone Decanoate can suppress natural testosterone production, leading to hypogonadism, testicular atrophy, and infertility. Post-cycle therapy (PCT) may be necessary to restore normal testosterone levels after discontinuation.
5. Fluid Retention: Nandrolone can cause fluid retention, which may exacerbate underlying cardiovascular or renal conditions.
ADVERSE REACTIONS
Common adverse reactions:
- Acne
- Oily skin
- Hair loss (androgenic alopecia)
- Increased libido or mood changes
Serious adverse reactions:
- Hepatotoxicity: Liver enzyme elevations, jaundice.
- Cardiovascular: Increased risk of heart attack, stroke, or hypertension.
- Endocrine: Gynecomastia (in men), testicular atrophy, or suppression of natural testosterone.
- Virilization (in women): Deepening of the voice, clitoral enlargement, or hirsutism.
INTERACTIONS
1. Anticoagulants: Nandrolone may enhance the effects of anticoagulants (e.g., warfarin), increasing the risk of bleeding. Regular monitoring of coagulation parameters is necessary.
2. Insulin and Oral Antidiabetics: Nandrolone can affect glucose metabolism and may require adjustments to insulin or antidiabetic medication dosages.
3. Corticosteroids: Combined use of corticosteroids with nandrolone may increase the risk of fluid retention and electrolyte imbalances.
USE IN SPECIFIC POPULATIONS
Pregnancy and Lactation: Nandrolone Decanoate is contraindicated in pregnant and breastfeeding women due to its potential teratogenic effects (Pregnancy Category X).
Pediatric Use: Use in children and adolescents is not recommended, as it may interfere with growth and cause premature closure of the growth plates (epiphyseal closure).
Geriatric Use: Elderly patients may be at increased risk of adverse effects, especially on the liver and cardiovascular system. Use with caution in elderly patients.
OVERDOSAGE
There is no specific antidote for nandrolone overdose. In the event of an overdose, supportive and symptomatic treatment should be provided. Monitor cardiovascular health and liver function.
STORAGE
Store below 25°C (77°F). Protect from light. Do not refrigerate or freeze. Keep out of reach of children.
PACKAGING
Nandrolone Decanoate 250 mg is supplied in 10 mL vials, each containing 250 mg of nandrolone decanoate in an oil-based solution.
MANUFACTURER
Oxydine Metabolics Switzerland
Oxydine.org
Hi@Oxydine.org
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